What are the common causes of liver failure that lead to transplant?

Common causes include chronic hepatitis (B or C), alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD/NASH), primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), autoimmune hepatitis, genetic disorders (e.g., alpha-1 antitrypsin deficiency), and acute liver failure due to drug overdose or viral infection.

What is the liver transplant process like?

The process involves evaluation, being placed on a waiting list, receiving a donor liver, undergoing surgery, and then lifelong immunosuppression and follow-up care. Evaluation includes extensive medical testing and psychosocial assessment. Matching is based on blood type and body size. Post-transplant care focuses on preventing rejection and infection.

What are the risks and complications associated with liver transplantation?

Risks include bleeding, infection, blood clots, bile duct complications, rejection of the new liver, side effects from immunosuppressant medications (e.g., kidney problems, increased risk of certain cancers), and the potential need for re-transplantation.

What is the long-term outlook after a liver transplant?

With proper care and adherence to the medication regimen, the long-term outlook can be very good. Many recipients live for many years with a significantly improved quality of life. Regular follow-up appointments are crucial to monitor liver function and manage any complications.

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FAQs

Candidates typically have end-stage liver disease (ESLD) where the liver can no longer function adequately, and other medical treatments have failed. They must also be healthy enough to undergo major surgery and adhere to a strict post-transplant medication regimen. A thorough evaluation is performed to assess suitability.

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